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» Biological information as set-based complexity
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BMCBI
2005
150views more  BMCBI 2005»
13 years 5 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...
BMCBI
2005
201views more  BMCBI 2005»
13 years 5 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2005
157views more  BMCBI 2005»
13 years 5 months ago
Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome bro
Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotat...
Judith E. Stenger, Hong Xu, Carol Haynes, Elizabet...
BMCBI
2004
156views more  BMCBI 2004»
13 years 5 months ago
GeneXplorer: an interactive web application for microarray data visualization and analysis
Background: When publishing large-scale microarray datasets, it is of great value to create supplemental websites where either the full data, or selected subsets corresponding to ...
Christian A. Rees, Janos Demeter, John C. Matese, ...
BMCBI
2004
142views more  BMCBI 2004»
13 years 5 months ago
GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies
Background: Microarray and other high-throughput technologies are producing large sets of interesting genes that are difficult to analyze directly. Bioinformatics tools are needed...
Bing Zhang, Denise Schmoyer, Stefan Kirov, Jay Sno...