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BMCBI
2008
152views more  BMCBI 2008»
13 years 5 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
BMCBI
2011
12 years 11 months ago
Properties of Metabolic Graphs: Biological Organization or Representation Artifacts?
Background: Standard graphs, where each edge links two nodes, have been extensively used to represent the connectivity of metabolic networks. It is based on this representation th...
Wanding Zhou, Luay Nakhleh
BIB
2010
129views more  BIB 2010»
13 years 5 months ago
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
Peter D. Karp, Suzanne M. Paley, Markus Krummenack...
GCB
2004
Springer
101views Biometrics» more  GCB 2004»
13 years 10 months ago
Kleene's Theorem and the Solution of Metabolic Carbon Labeling Systems
: Carbon Labeling Systems (CLS) are large equation systems that describe the dynamics of labeled carbon atoms in a metabolic network. The rapid solution of these systems is the alg...
Nicole Isermann, Michael Weitzel, Wolfgang Wiecher...
KES
2007
Springer
13 years 11 months ago
A Hybrid Symbolic-Statistical Approach to Modeling Metabolic Networks
Biological systems consist of many components and interactions between them. In Systems Biology the principal problem is modeling complex biological systems and reconstructing inte...
Marenglen Biba, Stefano Ferilli, Nicola Di Mauro, ...