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JIB
2006
106views more  JIB 2006»
13 years 5 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
BMCBI
2005
86views more  BMCBI 2005»
13 years 5 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
PVLDB
2008
141views more  PVLDB 2008»
13 years 4 months ago
WebTables: exploring the power of tables on the web
The World-Wide Web consists of a huge number of unstructured documents, but it also contains structured data in the form of HTML tables. We extracted 14.1 billion HTML tables from...
Michael J. Cafarella, Alon Y. Halevy, Daisy Zhe Wa...
BMCBI
2010
123views more  BMCBI 2010»
13 years 8 days ago
Predicting conserved protein motifs with Sub-HMMs
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...
Kevin Horan, Christian R. Shelton, Thomas Girke
CHI
2011
ACM
12 years 8 months ago
Usability of car dashboard displays for elder drivers
The elder population is rising worldwide; in the US, no longer being able to drive is a significant marker of loss of independence. One of the approaches to helping elders drive m...
Seungjun Kim, Anind K. Dey, Joonhwan Lee, Jodi For...