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BMCBI
2008
135views more  BMCBI 2008»
13 years 5 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BIOSYSTEMS
2007
115views more  BIOSYSTEMS 2007»
13 years 5 months ago
Evolving fuzzy rules to model gene expression
This paper develops an algorithm that extracts explanatory rules from microarray data, which we treat as time series, using genetic programming (GP) and fuzzy logic. Reverse polis...
Ricardo Linden, Amit Bhaya
BIOINFORMATICS
2005
152views more  BIOINFORMATICS 2005»
13 years 4 months ago
Intervention in context-sensitive probabilistic Boolean networks
Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...
KDD
2009
ACM
230views Data Mining» more  KDD 2009»
13 years 9 months ago
Grouped graphical Granger modeling methods for temporal causal modeling
We develop and evaluate an approach to causal modeling based on time series data, collectively referred to as“grouped graphical Granger modeling methods.” Graphical Granger mo...
Aurelie C. Lozano, Naoki Abe, Yan Liu, Saharon Ros...