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ISBI
2011
IEEE
12 years 8 months ago
Boosting power to detect genetic associations in imaging using multi-locus, genome-wide scans and ridge regression
Most algorithms used for imaging genetics examine statistical effects of each individual genetic variant, one at a time. We developed a new approach, based on ridge regression, to...
Omid Kohannim, Derrek P. Hibar, Jason L. Stein, Ne...
ISBI
2011
IEEE
12 years 8 months ago
Principal components regression: Multivariate, gene-based tests in imaging genomics
In imaging genomics, there have been rapid advances in genome-wide, image-wide searches for genes that influence brain structure. Most efforts focus on univariate tests that treat...
Derrek P. Hibar, Jason L. Stein, Omid Kohannim, Ne...