The Protein Information Resource (PIR) serves as an integrated public resource of functional annotation of protein data to support genomic/proteomic research and scientific discov...
Cathy H. Wu, Hongzhan Huang, Leslie Arminski, Jorg...
Protein domains are the building blocks of proteins, and their interactions are crucial in forming stable protein-protein interactions (PPI) and take part in many cellular processe...
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...