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» CLUSS: Clustering of protein sequences based on a new simila...
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BMCBI
2010
123views more  BMCBI 2010»
13 years 5 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2005
124views more  BMCBI 2005»
13 years 5 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
BMCBI
2006
169views more  BMCBI 2006»
13 years 5 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
BMCBI
2010
177views more  BMCBI 2010»
13 years 5 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman
NAR
2008
122views more  NAR 2008»
13 years 5 months ago
SIMAP - structuring the network of protein similarities
Protein sequences are the most important source of evolutionary and functional information for new proteins. In order to facilitate the computationally intensive tasks of sequence...
Thomas Rattei, Patrick Tischler, Roland Arnold, Fr...