20 search results - page 2 / 4 » CONAN: copy number variation analysis software for genome-wi... |
BMCBI
2010
13 years 5 months ago
2010
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
BMCBI
2007
13 years 5 months ago
2007
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
BMCBI
2008
13 years 5 months ago
2008
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
BMCBI
2010
13 years 5 months ago
2010
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
BMCBI
2010
13 years 5 months ago
2010
Background: Despite the recent success of genome-wide association studies in identifying novel loci contributing effects to complex human traits, such as type 2 diabetes and obesi...