Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
To investigate molecular-biological causes and effects of diseases and their therapies it becomes increasingly important to combine data from clinical trials with high volumes of e...
Background: Development of robust and efficient methods for analyzing and interpreting high dimension gene expression profiles continues to be a focus in computational biology. Th...
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
Anneleen Daemen, Olivier Gevaert, Karin Leunen, Va...
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen