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BMCBI
2007
166views more  BMCBI 2007»
13 years 6 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
BMCBI
2006
96views more  BMCBI 2006»
13 years 6 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
EC
2006
163views ECommerce» more  EC 2006»
13 years 6 months ago
An Extension of Geiringer's Theorem for a Wide Class of Evolutionary Search Algorithms
The frequency with which various elements of the search space of a given evolutionary algorithm are sampled is affected by the family of recombination (reproduction) operators. Th...
Boris Mitavskiy, Jonathan E. Rowe
BMCBI
2005
117views more  BMCBI 2005»
13 years 5 months ago
Graph-representation of oxidative folding pathways
Background: The process of oxidative folding combines the formation of native disulfide bond with conformational folding resulting in the native three-dimensional fold. Oxidative ...
Vilmos Ágoston, Masa Cemazar, Lászl&...
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...