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» Chaining Algorithms for Alignment of Draft Sequence
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BMCBI
2006
96views more  BMCBI 2006»
13 years 5 months ago
Structure alignment based on coding of local geometric measures
Background: A structure alignment method based on a local geometric property is presented and its performance is tested in pairwise and multiple structure alignments. In this appr...
Peter L. Chang, Andrew W. Rinne, T. Gregory Dewey
CORR
2007
Springer
81views Education» more  CORR 2007»
13 years 5 months ago
Faster exon assembly by sparse spliced alignment
Assembling a gene from candidate exons is an important problem in computational biology. Among the most successful approaches to this problem is spliced alignment, proposed by Gelf...
Alexandre Tiskin
BMCBI
2006
159views more  BMCBI 2006»
13 years 5 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2011
12 years 9 months ago
Improving pan-genome annotation using whole genome multiple alignment
Background: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations c...
Samuel V. Angiuoli, Julie C. Dunning Hotopp, Steve...
ALMOB
2007
151views more  ALMOB 2007»
13 years 5 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...