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» ChemAlign: Biologically Relevant Multiple Sequence Alignment...
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BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
13 years 10 months ago
ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties
—We present a new algorithm, ChemAlign, that uses physicochemical properties and secondary structure elements to create biologically relevant multiple sequence alignments (MSAs)....
Hyrum Carroll, Mark J. Clement, Quinn Snell, David...
BMCBI
2008
111views more  BMCBI 2008»
13 years 3 months ago
SciDBMaker: new software for computer-aided design of specialized biological databases
Background: The exponential growth of research in molecular biology has brought concomitant proliferation of databases for stocking its findings. A variety of protein sequence dat...
Riadh Hammami, Abdelmajid Zouhir, Karim Naghmouchi...
BMCBI
2010
147views more  BMCBI 2010»
13 years 3 months ago
Automatic detection of anchor points for multiple sequence alignment
Background: Determining beforehand specific positions to align (anchor points) has proved valuable for the accuracy of automated multiple sequence alignment (MSA) software. This f...
Florian Pitschi, Claudine Devauchelle, Eduardo Cor...
BMCBI
2010
121views more  BMCBI 2010»
13 years 3 months ago
MS4 - Multi-Scale Selector of Sequence Signatures: An alignment-free method for classification of biological sequences
Background: While multiple alignment is the first step of usual classification schemes for biological sequences, alignment-free methods are being increasingly used as alternatives...
Eduardo Corel, Florian Pitschi, Ivan Laprevotte, G...
BMCBI
2011
12 years 10 months ago
A discriminative method for family-based protein remote homology detection that combines inductive logic programming and proposi
Background: Remote homology detection is a hard computational problem. Most approaches have trained computational models by using either full protein sequences or multiple sequenc...
Juliana S. Bernardes, Alessandra Carbone, Gerson Z...