22 search results - page 4 / 5 » ChemAlign: Biologically Relevant Multiple Sequence Alignment... |
BMCBI
2006
13 years 5 months ago
2006
Background: Existing biological databases support a variety of queries such as keyword or definition search. However, they do not provide any measure of relevance for the instance...
BMCBI
2006
13 years 5 months ago
2006
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
BMCBI
2010
13 years 5 months ago
2010
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
BMCBI
2005
13 years 4 months ago
2005
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
BMCBI
2008
13 years 5 months ago
2008
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...