10 search results - page 1 / 2 » Chromosomal Breakpoint Detection in Human Cancer |
EVOW
2003
Springer
13 years 9 months ago
2003
Springer
Chromosomal aberrations are differences in DNA sequence copy number of chromosome regions 3 . These differences may be crucial genetic events in the development and progression o...
RECOMB
2003
Springer
14 years 4 months ago
2003
Springer
Although analysis of genome rearrangements was pioneered by Dobzhansky and Sturtevant 65 years ago, we still know very little about the rearrangement events that produced the exis...
BMCBI
2011
12 years 8 months ago
2011
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
KES
2008
Springer
13 years 3 months ago
2008
Springer
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
BMCBI
2006
13 years 4 months ago
2006
Background: DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterati...