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BMCBI
2006
160views more  BMCBI 2006»
13 years 5 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
BMCBI
2006
144views more  BMCBI 2006»
13 years 5 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
BMCBI
2006
131views more  BMCBI 2006»
13 years 5 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller
SIGOPS
2008
119views more  SIGOPS 2008»
13 years 5 months ago
Project Kittyhawk: building a global-scale computer: Blue Gene/P as a generic computing platform
This paper describes Project Kittyhawk, an undertaking at IBM Research to explore the construction of a nextgeneration platform capable of hosting many simultaneous web-scale work...
Jonathan Appavoo, Volkmar Uhlig, Amos Waterland
SP
2008
IEEE
122views Security Privacy» more  SP 2008»
13 years 5 months ago
Large-scale phylogenetic analysis on current HPC architectures
Abstract. Phylogenetic inference is considered a grand challenge in Bioinformatics due to its immense computational requirements. The increasing popularity and availability of larg...
Michael Ott, Jaroslaw Zola, Srinivas Aluru, Andrew...