39 search results - page 1 / 8 » CoSMoS: Conserved Sequence Motif Search in the proteome |
BMCBI
2006
13 years 4 months ago
2006
Background: With the ever-increasing number of gene sequences in the public databases, generating and analyzing multiple sequence alignments becomes increasingly time consuming. N...
BMCBI
2010
13 years 4 months ago
2010
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
BMCBI
2008
13 years 4 months ago
2008
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
BMCBI
2007
13 years 4 months ago
2007
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
BMCBI
2010
12 years 11 months ago
2010
Background: Profile HMMs (hidden Markov models) provide effective methods for modeling the conserved regions of protein families. A limitation of the resulting domain models is th...