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» Combination of scoring schemes for protein docking
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BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
13 years 5 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
13 years 12 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
ALMOB
2007
74views more  ALMOB 2007»
13 years 5 months ago
Evaluating deterministic motif significance measures in protein databases
Background: Assessing the outcome of motif mining algorithms is an essential task, as the number of reported motifs can be very large. Significance measures play a central role in...
Pedro Gabriel Ferreira, Paulo J. Azevedo
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2010
104views more  BMCBI 2010»
13 years 5 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton