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BMCBI
2007
95views more  BMCBI 2007»
13 years 5 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim
CORR
2007
Springer
108views Education» more  CORR 2007»
13 years 5 months ago
Combining haplotypers
Matti Kääriäinen, Niels Landwehr, S...
BMCBI
2008
138views more  BMCBI 2008»
13 years 5 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
BMCBI
2010
125views more  BMCBI 2010»
13 years 5 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2007
165views more  BMCBI 2007»
13 years 5 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...