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IJBRA
2007
97views more  IJBRA 2007»
13 years 5 months ago
Structural Risk Minimisation based gene expression profiling analysis
: For microarray based cancer classification, feature selection is a common method for improving classifier generalisation. Most wrapper methods use cross validation methods to eva...
Xue-wen Chen, Byron Gerlach, Dechang Chen, ZhenQiu...
BMCBI
2011
12 years 8 months ago
Evaluating methods for ranking differentially expressed genes applied to MicroArray Quality Control data
Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
Koji Kadota, Kentaro Shimizu
BMCBI
2008
190views more  BMCBI 2008»
13 years 5 months ago
Which missing value imputation method to use in expression profiles: a comparative study and two selection schemes
Background: Gene expression data frequently contain missing values, however, most downstream analyses for microarray experiments require complete data. In the literature many meth...
Guy N. Brock, John R. Shaffer, Richard E. Blakesle...
BMCBI
2010
108views more  BMCBI 2010»
13 years 5 months ago
Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of h
Background: A major goal of the analysis of high-dimensional RNA expression data from tumor tissue is to identify prognostic signatures for discriminating patient subgroups. For t...
Birte Hellwig, Jan G. Hengstler, Marcus Schmidt, M...
NAR
2008
174views more  NAR 2008»
13 years 3 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...