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BMCBI
2006
121views more  BMCBI 2006»
13 years 6 months ago
Robust computational reconstitution - a new method for the comparative analysis of gene expression in tissues and isolated cell
Background: Biological tissues consist of various cell types that differentially contribute to physiological and pathophysiological processes. Determining and analyzing cell type-...
Martin Hoffmann, Dirk Pohlers, Dirk Koczan, Hans-J...
BMCBI
2008
134views more  BMCBI 2008»
13 years 6 months ago
Clustering cancer gene expression data: a comparative study
Background The use of clustering methods for the discovery of cancer subtypes has drawn a great deal of attention in the scientific community. While bioinformaticians have propose...
Marcílio Carlos Pereira de Souto, Ivan G. C...
BMCBI
2010
243views more  BMCBI 2010»
13 years 6 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2010
147views more  BMCBI 2010»
13 years 6 months ago
Indirect two-sided relative ranking: a robust similarity measure for gene expression data
Background: There is a large amount of gene expression data that exists in the public domain. This data has been generated under a variety of experimental conditions. Unfortunatel...
Louis Licamele, Lise Getoor
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...