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CEC
2011
IEEE
12 years 5 months ago
Comparing alternative energy functions for the HP model of protein structure prediction
Abstract—Protein structure prediction is the problem of finding the functional conformation of a protein given only its amino uence. The HP lattice model is an abstract formulat...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
EVOW
2012
Springer
12 years 22 days ago
Multiobjectivizing the HP Model for Protein Structure Prediction
Abstract. The hydrophobic-polar (HP) model for protein structure preabstracts the fact that hydrophobic interactions are a dominant force in the protein folding process. This model...
Mario Garza-Fabre, Eduardo Rodriguez-Tello, Gregor...
BMCBI
2007
216views more  BMCBI 2007»
13 years 5 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
AE
2005
Springer
13 years 10 months ago
An Enhanced Genetic Algorithm for Protein Structure Prediction Using the 2D Hydrophobic-Polar Model
This paper presents an enhanced genetic algorithm for the protein structure prediction problem. A new fitness function, that uses the concept of radius of gyration, is proposed. Al...
Heitor S. Lopes, Marcos P. Scapin
BMCBI
2006
165views more  BMCBI 2006»
13 years 5 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...