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BMCBI
2005
96views more  BMCBI 2005»
13 years 4 months ago
Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity
Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Fran Supek, Kristian Vlahovicek
ALMOB
2006
135views more  ALMOB 2006»
13 years 4 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
BMCBI
2006
156views more  BMCBI 2006»
13 years 4 months ago
Score-based prediction of genomic islands in prokaryotic genomes using hidden Markov models
Background: Horizontal gene transfer (HGT) is considered a strong evolutionary force shaping the content of microbial genomes in a substantial manner. It is the difference in spee...
Stephan Waack, Oliver Keller, Roman Asper, Thomas ...
BMCBI
2010
158views more  BMCBI 2010»
13 years 5 months ago
Validation of differential gene expression algorithms: Application comparing fold-change estimation to hypothesis testing
Background: Sustained research on the problem of determining which genes are differentially expressed on the basis of microarray data has yielded a plethora of statistical algorit...
Corey M. Yanofsky, David R. Bickel
BMCBI
2008
128views more  BMCBI 2008»
13 years 5 months ago
Efficient computation of absent words in genomic sequences
Background: Analysis of sequence composition is a routine task in genome research. Organisms are characterized by their base composition, dinucleotide relative abundance, codon us...
Julia Herold, Stefan Kurtz, Robert Giegerich