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BMCBI
2008
146views more  BMCBI 2008»
13 years 5 months ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
BMCBI
2007
197views more  BMCBI 2007»
13 years 5 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
IJDMB
2007
119views more  IJDMB 2007»
13 years 4 months ago
Simulation study in Probabilistic Boolean Network models for genetic regulatory networks
: Probabilistic Boolean Network (PBN) is widely used to model genetic regulatory networks. Evolution of the PBN is according to the transition probability matrix. Steady-state (lon...
Shuqin Zhang, Wai-Ki Ching, Michael K. Ng, Tatsuya...
BIOINFORMATICS
2005
152views more  BIOINFORMATICS 2005»
13 years 4 months ago
Intervention in context-sensitive probabilistic Boolean networks
Motivation: Intervention in a gene regulatory network is used to help it avoid undesirable states, such as those associated with a disease. Several types of intervention have been...
Ranadip Pal, Aniruddha Datta, Michael L. Bittner, ...
BMCBI
2005
189views more  BMCBI 2005»
13 years 4 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen