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» Comparison study on k-word statistical measures for protein:...
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BMCBI
2007
122views more  BMCBI 2007»
13 years 5 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2010
167views more  BMCBI 2010»
13 years 5 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
BMCBI
2010
133views more  BMCBI 2010»
13 years 5 months ago
Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
Shandar Ahmad, Yumlembam Hemjit Singh, Yogesh Paud...
CN
2004
129views more  CN 2004»
13 years 5 months ago
Measuring normality in HTTP traffic for anomaly-based intrusion detection
In this paper, the problem of measuring normality in HTTP traffic for the purpose of anomaly-based network intrusion detection is addressed. The work carried out is expressed in t...
Juan M. Estévez-Tapiador, Pedro Garcia-Teod...
BMCBI
2010
156views more  BMCBI 2010»
13 years 5 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...