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» Complexity Estimation of Genetic Sequences Using Information...
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BIOINFORMATICS
2005
85views more  BIOINFORMATICS 2005»
13 years 5 months ago
An automated genotyping system for analysis of HIV-1 and other microbial sequences
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
Tulio de Oliveira, Koen Deforche, Sharon Cassol, M...
BMCBI
2010
124views more  BMCBI 2010»
13 years 5 months ago
Estimating time since infection in early homogeneous HIV-1 samples using a poisson model
Background: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homo...
Elena E. Giorgi, Bob Funkhouser, Gayathri Athreya,...
BMCBI
2008
214views more  BMCBI 2008»
13 years 3 months ago
Enhanced Bayesian modelling in BAPS software for learning genetic structures of populations
Background: During the most recent decade many Bayesian statistical models and software for answering questions related to the genetic structure underlying population samples have...
Jukka Corander, Pekka Marttinen, Jukka Siré...
BMCBI
2010
151views more  BMCBI 2010»
13 years 5 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...
BMCBI
2006
111views more  BMCBI 2006»
13 years 5 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...