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BMCBI
2011
12 years 9 months ago
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in Bre
Background: Elucidating the exact relationship between gene copy number and expression would enable identification of regulatory mechanisms of abnormal gene expression and biologi...
Hiroko K. Solvang, Ole Christian Lingjærde, ...
BMCBI
2006
98views more  BMCBI 2006»
13 years 5 months ago
The Secrets of a Functional Synapse - From a Computational and Experimental Viewpoint
Background: Neuronal communication is tightly regulated in time and in space. The neuronal transmission takes place in the nerve terminal, at a specialized structure called the sy...
Michal Linial
NAR
2000
172views more  NAR 2000»
13 years 5 months ago
The Molecular Biology Database Collection: an online compilation of relevant database resources
The Molecular Biology Database Collection represents an effort geared at making molecular biology database resources more accessible to biologists. This online resource, available...
Andreas D. Baxevanis
BMCBI
2007
112views more  BMCBI 2007»
13 years 5 months ago
Inferring biological functions and associated transcriptional regulators using gene set expression coherence analysis
Background: Gene clustering has been widely used to group genes with similar expression pattern in microarray data analysis. Subsequent enrichment analysis using predefined gene s...
Tae-Min Kim, Yeun-Jun Chung, Mun-Gan Rhyu, Myeong ...
BMCBI
2010
144views more  BMCBI 2010»
13 years 5 months ago
Super-sparse principal component analyses for high-throughput genomic data
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
Donghwan Lee, Woojoo Lee, Youngjo Lee, Yudi Pawita...