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BMCBI
2006
87views more  BMCBI 2006»
13 years 5 months ago
Computational expression deconvolution in a complex mammalian organ
Background: Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be used to...
Min Wang, Stephen R. Master, Lewis A. Chodosh
BMCBI
2008
155views more  BMCBI 2008»
13 years 5 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
TIP
2008
104views more  TIP 2008»
13 years 4 months ago
A Fast Thresholded Landweber Algorithm for Wavelet-Regularized Multidimensional Deconvolution
We present a fast variational deconvolution algorithm that minimizes a quadratic data term subject to a regularization on the 1 -norm of the wavelet coefficients of the solution. ...
Cédric Vonesch, Michael Unser
NIPS
2004
13 years 6 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
CORR
2000
Springer
112views Education» more  CORR 2000»
13 years 4 months ago
Evolution of differentiated expression patterns in digital organisms
Abstract. We investigate the evolutionary processes behind the development and optimization of multiple threads of execution in digital organisms using the avida platform, a softwa...
Charles Ofria, Christoph Adami, Travis C. Collier,...