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RECOMB
2004
Springer
14 years 4 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
ALMOB
2006
155views more  ALMOB 2006»
13 years 4 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2006
114views more  BMCBI 2006»
13 years 4 months ago
BLISS: biding site level identification of shared signal-modules in DNA regulatory sequences
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
Hailong Meng, Arunava Banerjee, Lei Zhou
NAR
2011
199views Computer Vision» more  NAR 2011»
12 years 7 months ago
RepTar: a database of predicted cellular targets of host and viral miRNAs
Computational identification of putative microRNA (miRNA) targets is an important step towards elucidating miRNA functions. Several miRNA target-prediction algorithms have been de...
Naama Elefant, Amnon Berger, Harel Shein, Matan Ho...
BMCBI
2006
116views more  BMCBI 2006»
13 years 4 months ago
Gene annotation and network inference by phylogenetic profiling
Background: Phylogenetic analysis is emerging as one of the most informative computational methods for the annotation of genes and identification of evolutionary modules of functi...
Jie Wu, Zhenjun Hu, Charles DeLisi