Sciweavers

4 search results - page 1 / 1
» Computational models with thermodynamic and composition feat...
Sort
View
BMCBI
2006
123views more  BMCBI 2006»
13 years 4 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2006
92views more  BMCBI 2006»
13 years 4 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
BMCBI
2007
139views more  BMCBI 2007»
13 years 4 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
ESCIENCE
2006
IEEE
13 years 8 months ago
Scientific Workflows: More e-Science Mileage from Cyberinfrastructure
We view scientific workflows as the domain scientist's way to harness cyberinfrastructure for e-Science. Domain scientists are often interested in "end-to-end" fram...
Bertram Ludäscher, Shawn Bowers, Timothy M. M...