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» Computer-Aided Peptide Evolution for Virtual Drug Design
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GECCO
2004
Springer
13 years 10 months ago
Computer-Aided Peptide Evolution for Virtual Drug Design
Ignasi Belda, Xavier Llorà, Marc Martinell,...
BMCBI
2007
113views more  BMCBI 2007»
13 years 5 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
CCE
2011
12 years 12 months ago
Computational energy-based redesign of robust proteins
The robustness of a system is a property that pervades all aspects of Nature. The ability of a system to adapt itself to perturbations due to internal and external agents, to agin...
Giovanni Stracquadanio, Giuseppe Nicosia
BMCBI
2010
151views more  BMCBI 2010»
13 years 5 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...