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» Conserved RNA secondary structures in viral genomes: A surve...
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BMCBI
2008
123views more  BMCBI 2008»
13 years 5 months ago
Shape based indexing for faster search of RNA family databases
Background: Most non-coding RNA families exert their function by means of a conserved, common secondary structure. The Rfam data base contains more than five hundred structurally ...
Stefan Janssen, Jens Reeder, Robert Giegerich
BMCBI
2008
162views more  BMCBI 2008»
13 years 5 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
ALMOB
2006
155views more  ALMOB 2006»
13 years 5 months ago
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expres...
Jonathan E. Allen, Steven L. Salzberg
BMCBI
2005
125views more  BMCBI 2005»
13 years 5 months ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...