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BMCBI
2005
223views more  BMCBI 2005»
13 years 5 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
BMCBI
2007
132views more  BMCBI 2007»
13 years 5 months ago
Analysis of probe level patterns in Affymetrix microarray data
Background: Microarrays have been used extensively to analyze the expression profiles for thousands of genes in parallel. Most of the widely used methods for analyzing Affymetrix ...
Alexander C. Cambon, Abdelnaby Khalyfa, Nigel G. F...
BMCBI
2006
102views more  BMCBI 2006»
13 years 5 months ago
Microarray analysis distinguishes differential gene expression patterns from large and small colony Thymidine kinase mutants of
Background: The Thymidine kinase (Tk) mutants generated from the widely used L5178Y mouse lymphoma assay fall into two categories, small colony and large colony. Cells from the la...
Tao Han, Jianyong Wang, Weida Tong, Martha M. Moor...
BMCBI
2008
167views more  BMCBI 2008»
13 years 5 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2011
12 years 8 months ago
A Simple Approach to Ranking Differentially Expressed Gene Expression Time Courses through Gaussian Process Regression
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
Alfredo A. Kalaitzis, Neil D. Lawrence