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» Correction of scaling mismatches in oligonucleotide microarr...
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BMCBI
2010
121views more  BMCBI 2010»
13 years 9 days ago
G-stack modulated probe intensities on expression arrays - sequence corrections and signal calibration
Background: The brightness of the probe spots on expression microarrays intends to measure the abundance of specific mRNA targets. Probes with runs of at least three guanines (G) ...
Mario Fasold, Peter F. Stadler, Hans Binder
BMCBI
2006
123views more  BMCBI 2006»
13 years 5 months ago
How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different result
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
Frank F. Millenaar, John Okyere, Sean T. May, Mart...
BMCBI
2007
200views more  BMCBI 2007»
13 years 5 months ago
Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
Ágnes Baross, Allen D. Delaney, H. Irene Li...
BIOINFORMATICS
2006
96views more  BIOINFORMATICS 2006»
13 years 5 months ago
Joint estimation of calibration and expression for high-density oligonucleotide arrays
Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...
BMCBI
2010
91views more  BMCBI 2010»
13 years 4 months ago
Washing scaling of GeneChip microarray expression
Background: Post-hybridization washing is an essential part of microarray experiments. Both the quality of the experimental washing protocol and adequate consideration of washing ...
Hans Binder, Knut Krohn, Conrad J. Burden