33 search results - page 6 / 7 » Correction of scaling mismatches in oligonucleotide microarr... |
BMCBI
2010
13 years 6 months ago
2010
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
BMCBI
2008
13 years 6 months ago
2008
Background: Most microarray studies are made using labelling with one or two dyes which allows the hybridization of one or two samples on the same slide. In such experiments, the ...
BMCBI
2004
13 years 5 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
BMCBI
2006
13 years 6 months ago
2006
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
BMCBI
2007
13 years 6 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...