Background: The most fundamental task using gene expression data in clinical oncology is to classify tissue samples according to their gene expression levels. Compared with tradit...
– In this paper we perform a t-test for significant gene expression analysis in different dimensions based on molecular profiles from microarray data, and compare several computa...
Krishna Yendrapalli, Ram B. Basnet, Srinivas Mukka...
Background: In the study of cancer genomics, gene expression microarrays, which measure thousands of genes in a single assay, provide abundant information for the investigation of...
Fan Shi, Christopher Leckie, Geoff MacIntyre, Izha...
Background: Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary ph...
Irina Dinu, John D. Potter, Thomas Mueller, Qi Liu...
Achieving high classification accuracy is a major challenge in the diagnosis of cancer types based on gene expression profiles. These profiles are notoriously noisy in that a larg...