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AINA
2006
IEEE
13 years 11 months ago
Partitioned optimization algorithms for multiple sequence alignment
Multiple sequence alignment is an important and difficult problem in molecular biology and bioinformatics. In this paper, we propose a partitioning approach that significantly impr...
Yixin Chen, Yi Pan, Juan Chen, Wei Liu, Ling Chen
SSDBM
2006
IEEE
163views Database» more  SSDBM 2006»
13 years 11 months ago
ACache: Using Caching to Improve the Performance of Multiple Sequence Alignments
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
Xun Tu, Kajal T. Claypool, Cindy X. Chen
BMCBI
2005
132views more  BMCBI 2005»
13 years 5 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer
GECCO
2005
Springer
112views Optimization» more  GECCO 2005»
13 years 10 months ago
A multiple objective evolutionary algorithm for multiple sequence alignment
The problem of multiple sequence alignment is important for bioinformatics. This problem is widely studied and a popular tool to solve this problem is Clustal X. This work introdu...
Pasut Seeluangsawat, Prabhas Chongstitvatana
EVOW
2010
Springer
13 years 8 months ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori