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» DNA Microarray Image Intensity Extraction using Eigenspots
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BMCBI
2006
103views more  BMCBI 2006»
13 years 5 months ago
Probe-level linear model fitting and mixture modeling results in high accuracy detection of differential gene expression
Background: The identification of differentially expressed genes (DEGs) from Affymetrix GeneChips arrays is currently done by first computing expression levels from the low-level ...
Sébastien Lemieux
BMCBI
2007
126views more  BMCBI 2007»
13 years 5 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
DAGSTUHL
2009
13 years 6 months ago
Learning Highly Structured Manifolds: Harnessing the Power of SOMs
Abstract. In this paper we elaborate on the challenges of learning manifolds that have many relevant clusters, and where the clusters can have widely varying statistics. We call su...
Erzsébet Merényi, Kadim Tasdemir, Li...