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BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
Improving the accuracy of protein secondary structure prediction using structural alignment
Background: The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve ...
Scott Montgomerie, Shan Sundararaj, Warren J. Gall...
BMCBI
2008
149views more  BMCBI 2008»
13 years 5 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
COMAD
2008
13 years 7 months ago
REBMEC: Repeat Based Maximum Entropy Classifier for Biological Sequences
An important problem in biological data analysis is to predict the family of a newly discovered sequence like a protein or DNA sequence, using the collection of available sequence...
Pratibha Rani, Vikram Pudi
BMCBI
2006
102views more  BMCBI 2006»
13 years 5 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 3 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...