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BMCBI
2010
133views more  BMCBI 2010»
13 years 5 months ago
Data analysis issues for allele-specific expression using Illumina's GoldenGate assay
Background: High-throughput measurement of allele-specific expression (ASE) is a relatively new and exciting application area for array-based technologies. In this paper, we explo...
Matthew E. Ritchie, Matthew S. Forrest, Antigone S...
BMCBI
2008
120views more  BMCBI 2008»
13 years 5 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2011
12 years 9 months ago
Genotype calling in tetraploid species from bi-allelic marker data using mixture models
Background: Automated genotype calling in tetraploid species was until recently not possible, which hampered genetic analysis. Modern genotyping assays often produce two signals, ...
Roeland E. Voorrips, Gerrit Gort, Ben Vosman
BMCBI
2011
13 years 19 days ago
GCOD - GeneChip Oncology Database
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...
Fenglong Liu, Joseph White, Corina Antonescu, John...
BMCBI
2008
100views more  BMCBI 2008»
13 years 5 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....