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» Decision problem for shuffled genes
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BMCBI
2006
72views more  BMCBI 2006»
13 years 5 months ago
Selecting effective siRNA sequences by using radial basis function network and decision tree learning
Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
BMCBI
2006
137views more  BMCBI 2006»
13 years 5 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2008
126views more  BMCBI 2008»
13 years 5 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
BMCBI
2006
153views more  BMCBI 2006»
13 years 5 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2005
106views more  BMCBI 2005»
13 years 5 months ago
Thesaurus-based disambiguation of gene symbols
Background: Massive text mining of the biological literature holds great promise of relating disparate information and discovering new knowledge. However, disambiguation of gene s...
Bob J. A. Schijvenaars, Barend Mons, Marc Weeber, ...