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BMCBI
2006
104views more  BMCBI 2006»
13 years 5 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
CDC
2009
IEEE
179views Control Systems» more  CDC 2009»
13 years 9 months ago
Bayesian network approach to understand regulation of biological processes in cyanobacteria
— Bayesian networks have extensively been used in numerous fields including artificial intelligence, decision theory and control. Its ability to utilize noisy and missing data ...
Thanura R. Elvitigala, Abhay K. Singh, Himadri B. ...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
13 years 5 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 5 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
BMCBI
2008
202views more  BMCBI 2008»
13 years 5 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...