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» Designing seeds for similarity search in genomic DNA
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RECOMB
2003
Springer
14 years 4 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
RECOMB
2004
Springer
14 years 4 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
BIBM
2009
IEEE
118views Bioinformatics» more  BIBM 2009»
13 years 8 months ago
Inexact Local Alignment Search over Suffix Arrays
We describe an algorithm for finding approximate seeds for DNA homology searches. In contrast to previous algorithms that use exact or spaced seeds, our approximate seeds may conta...
Mohammadreza Ghodsi, Mihai Pop
SIGMOD
2004
ACM
109views Database» more  SIGMOD 2004»
14 years 4 months ago
Piers: An Efficient Model for Similarity Search in DNA Sequence Databases
Growing interest in genomic research has resulted in the creation of huge biological sequence databases. In this paper, we present a hash-based pier model for efficient homology s...
Xia Cao, Shuai Cheng Li, Beng Chin Ooi, Anthony K....
BIRD
2008
Springer
13 years 6 months ago
Efficient Seeding Techniques for Protein Similarity Search
Abstract. We apply the concept of subset seeds proposed in [1] to similarity search in protein sequences. The main question studied is the design of efficient seed alphabets to con...
Mikhail A. Roytberg, Anna Gambin, Laurent No&eacut...