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BIB
2006
141views more  BIB 2006»
13 years 5 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
BMCBI
2006
120views more  BMCBI 2006»
13 years 5 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
BMCBI
2011
13 years 9 days ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
ICASSP
2007
IEEE
13 years 11 months ago
Protein Fold Recognition using Residue-Based Alignments of Sequence and Secondary Structure
Protein structure prediction aims to determine the three-dimensional structure of proteins form their amino acid sequences. When a protein does not have similarity (homology) to a...
Zafer Aydin, Hakan Erdogan, Yucel Altunbasak
CIBB
2008
13 years 7 months ago
Analysis of Kernel Based Protein Classification Strategies Using Pairwise Sequence Alignment Measures
Abstract. We evaluated methods of protein classification that use kernels built from BLAST output parameters. Protein sequences were represented as vectors of parameters (e.g. simi...
Dino Franklin, Somdutta Dhir, Sándor Pongor