44 search results - page 2 / 9 » Detecting Coevolution of Functionally Related Proteins for A... |
BMCBI
2007
13 years 4 months ago
2007
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
BMCBI
2006
13 years 4 months ago
2006
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
BIOINFORMATICS
2008
13 years 4 months ago
2008
Residue coevolution has recently emerged as an important concept, especially in the context of protein structures. While a multitude of different functions for quantifying it have...
NAR
2011
12 years 7 months ago
2011
We describe IsoBase, a database identifying functionally related proteins, across five major eukaryotic model organisms: Saccharomyces cerevisiae, Drosophila melanogaster, Caenorh...
BMCBI
2002
13 years 4 months ago
2002
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...