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BMCBI
2010
122views more  BMCBI 2010»
13 years 5 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
ICDE
2010
IEEE
399views Database» more  ICDE 2010»
14 years 19 days ago
Discovery-driven graph summarization
Abstract— Large graph datasets are ubiquitous in many domains, including social networking and biology. Graph summarization techniques are crucial in such domains as they can ass...
Ning Zhang, Yuanyuan Tian, Jignesh M. Patel
BMCBI
2007
122views more  BMCBI 2007»
13 years 5 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
NAR
2002
138views more  NAR 2002»
13 years 5 months ago
The KEGG databases at GenomeNet
The Kyoto Encyclopedia of Genes and Genomes (KEGG) is the primary database resource of the Japanese GenomeNet service (http://www.genome.ad.jp/) for understanding higher order fun...
Minoru Kanehisa, Susumu Goto, Shuichi Kawashima, A...
BMCBI
2010
106views more  BMCBI 2010»
13 years 5 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron