Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
Background: Statistical comparison of peptide profiles in biomarker discovery requires fast, userfriendly software for high throughput data analysis. Important features are flexib...
Mark K. Titulaer, Ivar Siccama, Lennard J. Dekker,...
Background: High-density short oligonucleotide microarrays are a primary research tool for assessing global gene expression. Background noise on microarrays comprises a significan...
Background: Various statistical scores have been proposed for evaluating the significance of genes that may exhibit differential expression between two or more controlled conditio...
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...