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TCS
2010
13 years 3 months ago
Detecting synchronisation of biological oscillators by model checking
We define a subclass of timed automata, called oscillator timed automata, suitable to model biological oscillators. Coupled biological oscillators may synchronise, as emerging be...
Ezio Bartocci, Flavio Corradini, Emanuela Merelli,...
ACSC
2010
IEEE
12 years 11 months ago
Average distance as a predictor of synchronisability in networks of coupled oscillators
The importance of networks of coupled oscillators is widely recognized. Such networks occur in biological systems like the heart, in chemical systems, in computational problems, a...
Anthony H. Dekker
BIOSYSTEMS
2008
72views more  BIOSYSTEMS 2008»
13 years 4 months ago
The manipulation of calcium oscillations by harnessing self-organisation
This paper investigates how self-organisation might be harnessed for the manipulation and control of calcium oscillations. Calcium signalling mechanisms are responsible for a numb...
Cristina Costa Santini, Andy M. Tyrrell
CMSB
2009
Springer
13 years 11 months ago
Modelling Biological Clocks with Bio-PEPA: Stochasticity and Robustness for the Neurospora crassa Circadian Network
Circadian clocks are biochemical networks, present in nearly all living organisms, whose function is to regulate the expression of specific mRNAs and proteins to synchronise rhyth...
Ozgur E. Akman, Federica Ciocchetta, Andrea Degasp...
GCB
2009
Springer
154views Biometrics» more  GCB 2009»
13 years 8 months ago
Comparative Identification of Differential Interactions from Trajectories of Dynamic Biological Networks
Abstract: It is often challenging to reconstruct accurately a complete dynamic biological network due to the scarcity of data collected in cost-effective experiments. This paper ad...
Zhengyu Ouyang, Mingzhou Song