10 search results - page 1 / 2 » Determinants of Antigenicity and Specificity in immune respo... |
BMCBI
2011
12 years 8 months ago
2011
Background: Target specific antibodies are pivotal for the design of vaccines, immunodiagnostic tests, studies on proteomics for cancer biomarker discovery, identification of prot...
BMCBI
2007
13 years 4 months ago
2007
Background: In an epitope-based vaccine setting, the use of conserved epitopes would be expected to provide broader protection across multiple strains, or even species, than epito...
BMCBI
2005
13 years 4 months ago
2005
Background: Recognition of microbial pathogens by plants triggers the hypersensitive reaction, a common form of programmed cell death in plants. These dying cells generate signals...
BMCBI
2008
13 years 4 months ago
2008
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
BMCBI
2008
13 years 4 months ago
2008
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...