Sciweavers

10 search results - page 2 / 2
» Determinants of Antigenicity and Specificity in immune respo...
Sort
View
BMCBI
2006
88views more  BMCBI 2006»
13 years 5 months ago
Protein kinases associated with the yeast phosphoproteome
Background: Protein phosphorylation is an extremely important mechanism of cellular regulation. A large-scale study of phosphoproteins in a whole-cell lysate of Saccharomyces cere...
Ross I. Brinkworth, Alan L. Munn, Bostjan Kobe
BMCBI
2010
141views more  BMCBI 2010»
13 years 5 months ago
CIG-DB: the database for human or mouse immunoglobulin and T cell receptor genes available for cancer studies
Background: Immunoglobulin (IG or antibody) and the T-cell receptor (TR) are pivotal proteins in the immune system of higher organisms. In cancer immunotherapy, the immune respons...
Yoji Nakamura, Tomoyoshi Komiyama, Motoki Furue, T...
BMCBI
2008
167views more  BMCBI 2008»
13 years 5 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2010
110views more  BMCBI 2010»
13 years 5 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2008
145views more  BMCBI 2008»
13 years 5 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...