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BMCBI
2010
142views more  BMCBI 2010»
13 years 4 months ago
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
Jongkwang Kim, Kai Tan
BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
13 years 10 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...
BIBE
2004
IEEE
115views Bioinformatics» more  BIBE 2004»
13 years 8 months ago
Discovering Novel Interacting Motif Pairs from Large Protein-Protein Interaction Datasets
Current motif discovery methods can only detect individual motifs in groups of protein sequences--they do not discover potentially-interacting motif pairs underlying the interacti...
Soon-Heng Tan, Wing-Kin Sung, See-Kiong Ng
ICDM
2009
IEEE
152views Data Mining» more  ICDM 2009»
13 years 11 months ago
SLIDER: Mining Correlated Motifs in Protein-Protein Interaction Networks
Correlated motif mining (CMM) is the problem to find overrepresented pairs of patterns, called motif pairs, in interacting protein sequences. Algorithmic solutions for CMM thereb...
Peter Boyen, Frank Neven, Dries Van Dyck, Aalt-Jan...
JMLR
2010
136views more  JMLR 2010»
12 years 11 months ago
Predicting the functions of proteins in Protein-Protein Interaction networks from global information
In this work we present a novel approach to predict the function of proteins in protein-protein interaction (PPI) networks. We classify existing approaches into inductive and tran...
Hossein Rahmani, Hendrik Blockeel, Andreas Bender